Bio: Mikhail Blagosklonny is a renowned Russian-American scientist best known for his pioneering work in the fields of oncology and aging research. He completed his MD and PhD at Saint Petersburg State University, where he first delved into the mechanisms underlying cellular processes and cancer. His early research focused on cell cycle regulation and cancer therapy.Blagosklonny is perhaps best known for his controversial and innovative theories on aging, particularly the “hyperfunction theory of aging.” This theory posits that aging is a result of the accumulation of damage caused by the overactivation of growth and metabolism pathways that, while beneficial in youth, become detrimental over time.
Supplement stack
- Rapamycin(6 mg of rapamycin per day)
Reason for taking this supplement: He has explored its potential for extending lifespan and reducing age-related diseases by inhibiting the TOR (Target of Rapamycin) pathway, which is involved in cell growth and metabolism.
- Resveratrol(3,000mg per day)
Reason for taking this supplement: Resveratrol is known for its potential anti-aging and longevity benefits. It is thought to activate certain longevity-related pathways, similar to the effects of caloric restriction.
- Metformin(500 mg two times a day taken with the morning and evening meals, or 850 mg a day taken with the morning meal)
Reason for taking this supplement: Metformin has been studied for its potential to extend lifespan and delay the onset of age-related diseases. It works through pathways related to metabolism and insulin sensitivity.
- Curcumin(Varies 500-10,000 mg per day)
Reason for taking this supplement:Curcumin has anti-inflammatory and antioxidant properties. It may support healthy aging by reducing inflammation and oxidative stress.
- Coenzyme Q10 (CoQ10) ( Varies 100-300 mg)
Reason for taking this supplement:This antioxidant is involved in cellular energy production and may help mitigate age-related declines in mitochondrial function.
- Nicotinamide Mononucleotide (NMN)(Varies 900-1,500 mg)
Reason for taking this supplement:NMN is a precursor to NAD+, a molecule involved in cellular energy and repair processes. It has been researched for its potential to support healthy aging and longevity.
- Vitamin D(1,000-3,000 IU or 25-100 mcg)
Reason for taking supplement : Vitamin D is essential for bone health and immune function,and also plays a role in aging and overall health.